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The mononuclear spot test or monospot test, a form of the heterophile antibody test, is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. The test is specific for heterophile antibodies produced by the human immune system in response to EBV infection. Commercially available test kits are 70–92% sensitive and 96–100% specific, wi…

Anticorpii heterofili sunt absenti in 10-20% din cazurile de mononucleoza infectioasa la adult, procentul fiind mai mare la copiii cu infectie manifesta. In aceste situatii, confirmarea。

Anticorpi anti-antigenul precoce (Anti-EA, Early Antigen) Anticorpi anti-antigenul nuclear EBV (EBNA, EBV Nuclear Antigen) CDC nu mai recomanda folosirea in practica。

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